Canine Genetics

Pedigree COI & Linebreeding Calculator

Estimate pedigree Coefficient of Inbreeding (Wright's COI) to safeguard canine genetic diversity and make informed breeding decisions.

1 Planned Mating (Sire x Dam)

Estimated Inbreeding Coefficient (COI)

Planned Litter

6.25%
Wright's Inbreeding Coefficient
Genetic Risk Level: Moderate Risk (6.25%–12.5% — Common in Purebred Linebreeding)
< 6.25% Low6.25–12.5% Moderate12.5–25% High> 25% Critical

🧬Scientific Insights on Inbreeding Co-efficient

Litter Size & Vigor

Litter Size & Fecundity: High COI (>12.5%) correlates with reduced average litter size and lowered puppy vigor.

Immune Complex (MHC)

Immune Competence: Higher heterozygosity (lower COI) strengthens the major histocompatibility complex (MHC) immune response.

Recessive Genetic Defects

Recessive Deleterious Alleles: Inbreeding doubles the probability of expressing dormant homozygous health defects.

Breeder Guideline

Breeder Action: Aim to keep planned litters below the breed average COI (typically under 6.25%–10% where possible).